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TAMSULOSIN HYDROCHLORIDE

Product Identification

Synonyms : (R)-5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzene-1- sulfonamide HCl
Chemical Structure :
Molecular Formula : C20H28N2O5S.HCl
Molecular Weight : 444.97
CAS NO. : [106463-17-6]

Specification

Appearance : White crystalline powder
Solubility : Slightly soluble in water, freely soluble in formic acid, slightly soluble in anhydrous ethanol
Identification by UV :

The IR spectrum of the sample shall be concordant with that of standard spectrum

By HPLC :

The retention time of the major peak of the sample corresponds to that of the standard by HPLC

By Chlorides

: Responds to the test for Chlorides
Specific Optical Rotation : Between -17.5 ° to -20.5 ° (on dry basis at 25 °C)
Loss on Drying (% w/w) : NMT 0.5% (at 105 °C ± 2 °C)
:

Between -17.5 ° to -20.5 °

Residue on ignition (%) : NMT 0.1%
Heavy metals (ppm) : NMT 20ppm
Chiral Purity
(Enantiomeric purity (%)
: NMT 0.1%
Assay (by Chemical method) : NLT 98.5% and NMT 101.0%         

Transportation

UN No. : Not regulated.
Hazardous Class : Not regulated.
Packing Group : Not regulated.

Packing & Storage

Packing : 20kg in Fibre drums
Storage : Store in a cool, dry place. Store in a tightly closed container

Application

  • Tamsualosin is used in the treatment of difficult urination, a common symptom of enlarged prostate. Tamsualosin, and other medications in the class called alpha blockers, work by relaxing bladder neck muscles and muscle fibers in the prostate itself and make it easier to urinate
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The information and recommendations in this publication are to the best of our knowledge reliable. However, nothing herein is to be construed as a warranty or representation. Users should make their own tests to determine the applicability of such information or the suitability of any products for their own particular Purpose. Statements concerning the use of the products described herein are not to be construed as recommending the infringement of any patent and no liability for infringement arising out of any such use is assumed.

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